A T1 and ECV phantom for global T1 mapping quality assurance: The T1 mapping and ECV standardisation in CMR (T1MES) program
نویسندگان
چکیده
Background Myocardial T1 and extracellular volume (ECV) estimates have applications in a range of myocardial diseases. Factors responsible for systematic inaccuracies in T1 mapping are beginning to be known but little is known about its delivery at ‘health-care system’ scale and there is no global quality assurance (QA) system. Agarose phantoms are common in MRI and nickel ions preferred for lower temperature sensitivity. This program aims to 1 Create a partnership to design 1.5/3T phantoms for any manufacturer/sequence reflecting myocardial/blood T1 pre/post-contrast 2 Test and mass produce phantoms to regulatory standards 3 Distribute globally 4 Analyse serial scans to understand T1 mapping at scale 5 Publish recipes 6 Explore delivery of a ‘T1/ECV Standard’ via local calibration We report results of steps 1-3.
منابع مشابه
A medical device-grade T1 and ECV phantom for global T1 mapping quality assurance—the T1 Mapping and ECV Standardization in cardiovascular magnetic resonance (T1MES) program
BACKGROUND T1 mapping and extracellular volume (ECV) have the potential to guide patient care and serve as surrogate end-points in clinical trials, but measurements differ between cardiovascular magnetic resonance (CMR) scanners and pulse sequences. To help deliver T1 mapping to global clinical care, we developed a phantom-based quality assurance (QA) system for verification of measurement stab...
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